Парахонский
Богдан
Владиславович
Парахонский
Богдан
Владиславович
Старший научный сотрудник
Образование:
Московский Государственный Университет имени М.В. Ломоносова, 2006 г.
Диссертации и учёные степени:
Кандидат физико-математических наук, Design of Microcontainers by Layer-by-Layer and Electropolymerisation Methods and Investigation of the Remote Release Process of Encapsulation Materials, 2009 г.
Трудовая биография:
2013-2014 postdoctoral fellow, department of Physics, University of Trento, Trento, Italy
Photoactive anticancer drugs based on vaterite particles.
2010-2013 Marie Curie Postdoctoral Fellow, BIOtech centre of the University of Trento, Trento, Italy;
Synthesis and applications of micro- and nanocontainers for drug delivery systems: from chemical synthesis to in vivo tests.
2011 Visiting researcher of ICEM centre, Kyoto University, Kyoto, Japan;
Application of the vaterite micro- and nanoparticles as delivery system to cardio cells.
2009 – 2010 Postdoctoral Fellow, Aveiro University, Aveiro, Portugal;
Formation of the smart anticorrosion coatings.
2007 – 2008 Visiting Researcher, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany;
Creation of the new type of conductive containers based on pyrrole electropolymerization and ultrasound treatment.
2006 – 2007 Visiting Researcher, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany;
Formation and investigation of the laser induced release from polyelectrolyte capsules.
2006 – 2010 Junior Researcher, Institute of Crystallography, Russian Academy of Sciences, Moscow, Russia;
Formation, modification and application of the polyelectrolyte capsules modified by plasmon-resonans nanoparticles.
2004 – 2006 Engineer, Institute of Crystallography, Russian Academy of Sciences, Moscow, Russia
Langmuir-Blodgett film preparation and structure analysis by X –ray reflectivity.
Премии и награды:
Young scientist award for the best poster, XI All-Russian Scientific Conference “Structure and Dynamics of Molecular Systems”, 2004 г.
DAAD (German Academic Exchange Service) scholarship. Project: Creating polymer nanocontainers for anticorrosion self-healing covers, 2007 г.
Tokyo Boeki (Rus) Award to the best PhD student of Physical Faculty of Lomonosov Moscow State University in 2007-2008 years, 2008 г.
Scholarship Marie Curie Co-funded project "Trentino - The Trentino programme of research training and mobility of post-doctoral researchers". Project: Synthesis of nanocontainers with multiple triggering release mechanism, 2010 г.
Institute of Crystallography award for young scientist for the work: “Modification of polyelectrolyte capsules for the mange of moving and control release. Using polyelectrolyte capsules for drug delivery to the central nerving system”, 2011 г.
Dr. Tasilo Prize, for the Best paper of author under 30, 4th International Conference NANOCON 2012, Brno Czech Republic, EU Title: “Biocompatible calcium carbonate particles: toward drug-delivery applications”, 2012 г.
Основные научные публикации:
Book
Refereed Journal Publications
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B. V. Parakhonskiy, A.M. Yashchenok, H. Möhwald, D. Volodkin, A.G. Skirtach, Release from Polyelectrolyte Multilayer Capsules in Solution and on Polymeric Surfaces, Adv. Mater. Interfaces. (2016). DOI: 10.1002/admi.201600273
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Y.I. Svenskaya, A.M. Pavlov, D.A. Gorin, D.J. Gould, B. V. Parakhonskiy, G.B. Sukhorukov, Photodynamic Therapy Platform Based on Localized Delivery of Photosensitizer By Vaterite Submicron Particles, Colloids Surfaces B Biointerfaces. 146 (2016) 171–179.
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S. Donatan, A.M. Yashchenok, N. Khan, B. V. Parakhonskiy, M. Cocquyt, B.-E.S. Pinchasik, et al., The loading capacity versus the enzyme activity in new anisotropic and spherical calcium carbonate microparticles, ACS Appl. Mater. Interfaces. (2016) DOI: acsami.6b03492.
- E.S. Prikhozhdenko, E.V. Lengert, B. V. Parakhonskiy, D.A. Gorin, G.B. Sukhorukov, A.M. Yashchenok, Biocompatible chitosan nanofibers functionalized with silver nanoparticles for sers based detection, Acta Phys. Pol. A. 129 (2016) 247–249. Open Access.
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E. Lengert, A.M. Yashchenok, V. Atkin, A. Lapanje, D.A. Gorin, G.B. Sukhorukov, B.V. Parakhonskiy, Hollow silver alginate microspheres for drug delivery and surface enhanced Raman scattering detection, RSC Adv. 6 (2016) 20447–20452.
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Bogdan V. Parakhonskiy, Yulia I. Svenskaya , Hassan A. Fattah, and Dmitry A. Gorin Preparation of porous calcium carbonate microparticles under the ultrasonic treatment //Advanced power technologie Volume 27, Issue 2, 2016, Pages 618–624
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Bogdan Parakhonskiy, D.Shchukin Polypyrrole microcontainers: electrochemic al synthesis and perspective application//Langmuir 2015, 31 (33), pp 9214–9218
- B. V. Parakhonskiy, M. V Zyuzin, A. Yashchenok, S. Carregal-Romero, J. Rejman, H. Möhwald, et al., The influence of the size and aspect ratio of anisotropic, porous CaCO3 particles on their uptake by cells, J. Nanobiotechnology. 13 (2015) 53. (Open access).
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A.N. Severyukhina, B. V. Parakhonskiy, E.S. Prikhozhdenko, D.A. Gorin, G.B. Sukhorukov, H. Möhwald, et al., Nanoplasmonic Chitosan Nanofibers as Effective SERS Substrate for Detection of Small Molecules, ACS Appl. Mater. Interfaces. 7 (2015) 15466–15473.
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A. Sergeeva, R. Sergeev, E. Lengert, A. Zakharevich, B. V. Parakhonskiy, D. Gorin, et al., Composite Magnetite and Protein Containing CaCO<inf>3</inf> Crystals. External Manipulation and Vaterite → Calcite Recrystallization-Mediated Release Performance, ACS Appl. Mater. Interfaces. 7 (2015) 21315–21325.
- Y. Svenskaya, D. Gorin, B. Parakhonskiy, G. Sukhorukov, Point-wise laser effect on NIH/3T3 cells impregnated with photosensitizer-loaded porous calcium carbonate microparticles, in: 2015 IEEE 15th Int. Conf. Nanotechnol., IEEE, 2015: pp. 1513–1516.
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Pieter Wuytens, Bogdan V. Parakhonskiy, Alexey M. Yashchenok, Mathias Winterhalter, Andre G. Skirtach Pharmacological aspects of membrane modulation – release from drug delivery carriers and transport across membranes //Current Opinion in Pharmacy, 2014, 18, 129–140.
- V. Parakhonskiy, A. M. Yashchenok, S. Donatan, F. Tessarolo, R. Antolini, H. Möhwald and A. G. Skirtach Controlling morphology of calcium carbonate particles: spherical, elliptical, star-like, and cubic configurations //ChemPhysChem 2014, Vol. 15, 2817-2822.
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Bogdan V. Parakhonskiy, Yulia I. Svenskaya , Alexey М. Yashchenok, Hassan A. Fattah, Olga A. Inozemtseva, Francesco Tessarolo, Renzo Antolini, and Dmitry A. Gorin Synthesis of size controlled hydroxyapatite particles using calcium carbonate templates and their application as SERS platform //Colloids and Surfaces B: Biointerfaces 2014, 118, 243-248.
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Bogdan V. Parakhonskiy, Alexey Yashchenok, Manfred Konrad, Andre G. Skirtach Colloidal Micro- and Nano- Particles as Templates for Polyelectrolyte Multilayer Capsules// Advanced in Colloids and Interfaces science 2014, Vol. 207, 253-264.
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Bogdan V. Parakhonskiy, Cristina Foss, Eleonora Carletti, Albrecht Haase, Antonella Motta, Claudio Migliaresi, Renzo Antolini Sub-micron vaterite containers for intracellular delivery providing tailored release by a crystal phase transition // Tailored intracellular delivery via a crystal phase transition in 400 nm vaterite particles, Sci.2013, Vol 1, 1273-1281.
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Svenskaya, Y., Parakhonskiy, B., Haase, A., Atkin, V., Lukyanets, E., Gorin, D., and Antolini, R. Anticancer drug delivery system based on calcium carbonate particles loaded with a photosensitizers, BioPhys. Chem. 2013, Vol. 182, 11-15.
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Alexey Yashchenok, Bogdan Parakhonskiy, Senem Donatan, Dorothee Kohler, Andre Skirtach, Helmuth Möhwald, “Polyelectrolyte multilayer microcapsules templated on spherical, elliptical and square calcium carbonate particles” // Journal of Materials Chemistry B 2013. Journal of Materials Chemistry B, 2013, Vol. 1, 1223-1228 (cover page).
- Bogdan V. Parakhonskiy, Francesco Tessarolo, Albrecht Haase, and Renzo Antolini Dependence of sub-micron vaterite container release properties on pH and ionic strength of the surrounding solution //Advance in science and technology, 2013, Vol. 86, 81-85. Open access
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Yashchenok, A. M.; Borisova, D.; Parakhonskiy, B. V.; Masic, A.; Pinchasic, B.-E.; Möhwald, H.; Skirtach, A. G. Nanoplasmonic smooth silica versus porous calcium carbonate bead biosensors for detection of biomarkers// Annalen der physik, 2012, Vol 10, 1–10 (cover page).
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Bogdan V. Parakhonskiy, Albrecht Haase, and Renzo Antolini, Sub-Micron vaterite Containers: Synthesis, Substance Loading, and Release// Angew. Chem. Int. Ed. 2012, Vol 51, No. 5, 1195-1197 (cover page). Impact factor: 13.73.
- Parakhonskiy, B., Haase, A., Piccoli, F., Caola, I., Tessarolo, F., Bukreeva, T., and Antolini, R. Porous vaterite particles as drug delivery system: synthesis, encapsulation, and controlled release// Eur. Biophys. J, 2011, Vol 40, No S1, 230.
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B.V. Parakhonskiy, M. F. Bedard T. V. Bukreeva, G. B. Sukhorukov, H. Mohwald, A. G. Skirtach Nanoparticles Distribution Control on Polyelectrolytes. Part II: Low Concentration Limit // J. Phys. Chem. C, 2010, Vol. 114, No 5, 1996–2002.
- Т.V. Bukreeva, I.V. Marchenko, B.V. Parakhonskiy, U.V. Grigoriev “Formation Of Silver Nanoparticles In Polyelectrolyte Capsules Shell By Silver Mirror Reaction ” // Colloid journal, 2009 ,Vol. 71, No. 5, 596–602.
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Bogdan Parakhonskiy, Daria Andreeva, Helmuth Mohwald, Dmitry G. Shchukin “Hollow Polypyrrole Containers with Regulated Uptake/Release Properties” //Langmuir, 2009, Vol. 25 No.8, 4780–4786.
- T.V. Bukreeva, B.V. Parakhonskiy, I.V. Marchenko, B.N. Khlebtcov, N.G. Khlebtcov, O.V. Dementieva, M.N. Savvateev, L.A. Feigin, M.N. Kovalchuk “Polyelectrolyte Microcapsules with a Shell Containing Silver and Gold Nanoparticles, Based on Calcium Carbonate and Polystyrene Cores” //Russian Nanotechnologies, Vol. 1-2, 2008, 85–93;
- T.V. Bukreeva, B.V. Parakhonsky, A.G. Skirtach, A.S. Susha, G.B. Sukhorukov. “Polyelectrolyte microcapsules formation with silver and gold nanoparticles in the shell and remote destruction of the capsules by laser irradiation” //Crystallography Reports. 2006. Vol.51. No.5, 863-869.
- T.V. Bukreeva, K.A. Dembo, I.V. Myagkov, B.V. Parakhonsky, L.A. Feigin. Formation of Langmuir-Blodgett superlattices consisting of bilayers of different metal stearates// The Journal of Surface Investigation. X-ray, Synchrotron and Neutron Techniques (Poverkhnost'. Rentgenovskie, Sinkhrotronnyei Neitronnye Issledovaniya) (in Russian) 2005, No.7, 23-29.
Conference Proceedings with peer review process
- B.V. Parakhonskiy, T.V. Bukreeva “A study of Laser Irradiation Influence on the Stable of Polyelectrolyte Micro- and Nanocapsules” //WDS'07 Proceedings of Contributed Papers, Part III, 2007, 118–122.
- Parakhonskiy B.V., Bukreeva T.V., Parakhonskiy G.V, Skirtach A.G., Sukhorukov G.B., Khlebtsov N.G., Feigin L.A., Kovalchuk M.V. “Permeability adjustment of polyelectrolyte micro- and nanocapsules by laser irradiation” // SPIE. 2007. V. 6536. P. 653605.
Дополнительная информация:
Specialised Expertise: Design, characterization and analysis of material for biomedical application.
Current project: Synthesis and applications of mic ro- and nanocontainers for drug delivery systems.
Reviewer of Journals:
• Journal of Colloids and Interfaces (Elsevier)
